Research

This article looks at the potential use of CBD oil as a primary treatment for lung cancer, based off a case study of an individual who declined conventional treatment for non-small cell lung cancer (NSCLC). The patient, a woman in her 80’s, was diagnosed with lung cancer in 2018 after observation of a 41mm lesion […]

The emergence of multi-drug resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) causes a major threat to public health due to its limited therapeutic options. There is an urgent need for the development of new effective antimicrobial agents and alternative strategies that are effective against resistant bacteria. This study aimed at the development of a […]

This paper reviews the basic research regarding the molecular mechanism of CBD’s action with particular focus on its analgesic potential for chronic pain treatment, as well as describing the detailed analgesic and anti-inflammatory effects of CBD in various models, including neuropathic pain, inflammatory pain, osteoarthritis and others. The referenced studies indicate a positive influence of […]

With the high availability of a non-intoxicating compound, cannabidiol (CBD) has generated heightened interest in its use in the field of oncology. This review focuses on the widespread therapeutic potential of CBD with regard to enhanced wound healing, lowered toxicity profiles of chemotherapy treatments, and augmented antitumorigenic effects. This study addresses the potential influence of […]

This article focuses on the potential use of CBD as a therapeutic for the cardiovascular system, a field where CBD has been theorised to be beneficial due to its antioxidant and anti-inflammatory properties. Other studies have shown that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of […]

The primary aim of this research paper was to investigate how CBD influences cerebral blood flow (CBF) in regions involved in memory processing. It was conducted under a randomised, crossover, double-blind design in which 15 healthy participants were administered CBD or a placebo on separate days. Regional CBF was measured at rest using arterial spin […]

There is a lot of research about the positive effects of CBD and Mental Health.  This report is a systematic analysis of a multitude of different research papers and conducted trials with regards to CBD’s impact on a multitude of different mental health conditions, covering social anxiety disorder (SAD), and autism spectrum disorder (ASD), as […]

This review summarizes the chemical and biological effects of cannabidiol (CBD) and its natural and synthetic derivatives, particularly in relation to the antioxidant and anti-inflammatory effects of CBD and its derivatives, bearing in mind the possibilities of using this phytocannabinoid to protect against oxidative stress and the consequences associated with oxidative modifications of proteins and […]

A runner’s high is a sense of well-being some people experience after prolonged exercise. For decades, it was hypothesized that exercise-induced endorphin release is solely responsible for a runner’s high, but recent evidence has suggested that endocannabinoids also may play a role. A popular belief has been that endogenous endorphins mediate the effects of a […]

This study looks at conditions such as Post-Traumatic Stress Disorder (PTSD) as well as other conditions stemming from fear, stress, and anxiety, through the targeting of Fatty Acid Amide Hydrolase (FAAH) to increase the efficiency of Anandamide’s (AEA) interactions with the ECS and different areas of the brain as a potential treatment for PTSD. Preclinical […]

In this study pertaining to cannabinoids and their potential usage as treatments for obesity and diabetes, CBD was looked at with particular interest in regards to any additional health issues that can come as a result of obesity in sites that have ties to the endocannabinoid system, namely the liver and the heart, however CBD’s […]

This study was looking at determining whether CBD helps improve sleep and/or anxiety in a clinical population. The sample initially consisted of 103 patients, however was reduced to 72 patients presenting primary concerns of anxiety (n=47) or poor sleep (n=25), where CBD was used as an adjunct to usual treatment. Nearly all patients were given […]

The aim of this research was to assess the effects of cannabidiol on different targets of the hypothalamus-pituitary-adrenal (HPA) axis under baseline stress conditions. Administered (5mg/kg, 15mg/kg, and 30mg/kg) 90 minutes before single restraint stress exposure, measurements were taken of alterations in the relative gene expressions of corticotropin-releasing factor in the paraventricular nucleus, pro-opiomelanocortin in […]

The primary purpose of this study was to investigate the anti-inflammatory effects of two of the non-psychotropic cannabinoids, cannabidiol (CBD) and Cannabigerol (CBG) alone and in combination, in a model of pulmonary inflammation. The results of the work suggest that the cannabinoids CBD and CBG in combination have significant anti-inflammatory activity in the lung. The […]

The aim of this study was to evaluate the effects of chronic treatment with CBD (10 mg/kg, i.p.) on PD‐associated neurodegenerative and neuro-inflammatory processes, and motor deficits in the 6‐hydroxydopamine model. Moreover, the article investigated the potential mechanisms by which CBD exerted its effects in this model. CBD‐treated animals showed a reduction of nigrostriatal degeneration […]

A macro-analysis of 49 different research papers (focusing primarily on animal studies) on the effects of CBD regarding multiple anxiety or stress-oriented disorders, such as Post-Traumatic Stress Disorder, Generalised Anxiety Disorder, and Social Anxiety Disorder to name a few. Preclinical evidence demonstrates CBD’s efficacy in reducing anxiety behaviours relevant to multiple stress and anxiety based […]