Cart

The Potential Use of Cannabidiol for the Treatment of Obesity and Diabetes

In this study pertaining to cannabinoids and their potential usage as treatments for obesity and diabetes, CBD was looked at with particular interest in regards to any additional health issues that can come as a result of obesity in sites that have ties to the endocannabinoid system, namely the liver and the heart, however CBD’s impact on other areas were inspected. With regards to each of these areas there were signs of CBD being of benefit to treating specific conditions.

For the liver, CBD showed a positive influence, namely the reduction of intracellular lipid content in the in vitro hepatosteatosis model, possibly by enhancing lipolysis and mitochondrial activity through increased fatty acids oxidation. Simultaneously, the it was observed that CBD enhanced the level of glutathione, adenosine triphosphate, and nicotinamide adenine dinucleotide, which supported the assumption that CBD increases intracellular lipolysis and mitochondrial activity. Additionally, results displayed that CBD attenuates liver steatosis, inflammatory response, oxidative/nitrative stress, and neutrophil infiltration in the liver.

For the heart, tests on human cardiomyocytes subject to a high glucose concentration as well as a mouse model of type 1 diabetic cardiomyopathy were analysed. It was demonstrated that CBD reduced cardiac fibrosis, myocardial oxidative/ nitrative stress, inflammation and cell death in diabetic hearts, as well as finding that CBD attenuated the high glucose-induced enhanced ROS (reactive oxygen species) generation and cell death in human cardiomyocytes.

Many studies indicated that CBD affects both lipid and glucose metabolism through the action on various receptors as well as several metabolites. From the existing data, it can be seen that CBD has the promising potential as a therapeutic agent and might be effective in alleviating the symptoms of insulin resistance, type 2 diabetes and metabolic syndrome.

 

Read report here

 

Goodbody has no association with the organisation that conducted this research and is not in a position to validate the research methods, results or conclusions of the published articleIt is provided for awareness of research available that may be of interest only. Any reader should read a range of articles and research to have a balanced and informed view.



Goodbody is a trading name of Goodbody Botanicals Ltd a member of the Sativa Wellness Group Inc.

Goodbody products are not intended to treat, diagnose, cure or prevent any disease. The information and products presented on this site are not intended for medical use nor do they make any medical claims. Always seek the advice of your physician or another qualified healthcare provider for any questions you have regarding a medical condition, and before undertaking any diet, exercise or other health related program.

Copyright © 2021 Goodbody Botanicals Ltd

Company

Goodbody Botanicals Ltd
The Blue Building
Stubbs Lane
Beckington
BA11 6TE


* For further details about the Sativa Wellness Group please click here