The Antimicrobial Activity of CBD

The emergence of multi-drug resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) causes a major threat to public health due to its limited therapeutic options. There is an urgent need for the development of new effective antimicrobial agents and alternative strategies that are effective against resistant bacteria. This study aimed at the development of a […]

Cannabidiol’s Use for Chronic Pain Treatment: A Review of Existing Literature

This paper reviews the basic research regarding the molecular mechanism of CBD’s action with particular focus on its analgesic potential, as well as describing the detailed analgesic and anti-inflammatory effects of CBD in various models, including neuropathic pain, inflammatory pain, osteoarthritis and others. The referenced studies indicate a positive influence of CBD in treatment for […]

Can Cannabidiol Impact the Efficacy of Chemotherapy and Alleviate the Side-Effects of Cancer Treatments?

With the high availability of a non-intoxicating compound, cannabidiol (CBD) has generated heightened interest in its use in the field of oncology. This review focuses on the widespread therapeutic potential of CBD with regard to enhanced wound healing, lowered toxicity profiles of chemotherapeutics, and augmented antitumorigenic effects. This study addresses the potential influence of regular […]

The Effects of Cannabidiol on the Cardiovascular System

This article focuses on the potential use of CBD as a therapeutic for the cardiovascular system, a field where CBD has been theorised to be beneficial due to its antioxidant and anti-inflammatory properties. Other studies have shown that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of […]

The Effects of Cannabidiol on Cerebral Blood Flow

The primary aim was to investigate how CBD influences cerebral blood flow (CBF) in regions involved in memory processing. It was conducted under a randomised, crossover, double-blind design in which 15 healthy participants were administered CBD or a placebo on separate days. Regional CBF was measured at rest using arterial spin labelling 3h after drug […]

CBD and Mental Health: A Systematic Analysis

This report is a systematic analysis of a multitude of different research papers and conducted trials with regards to CBD’s impact on a multitude of different mental health conditions, covering social anxiety disorder (SAD), and autism spectrum disorder (ASD), as well as attention deficit hyperactivity disorder (ADHD). This study collated case reports, case series, open-label […]

The Antioxidative and Anti-Inflammatory Properties of Cannabidiol

This review summarizes the chemical and biological effects of cannabidiol (CBD) and its natural and synthetic derivatives, particularly in relation to the antioxidant and anti-inflammatory effects of CBD and its derivatives, bearing in mind the possibilities of using this phytocannabinoid to protect against oxidative stress and the consequences associated with oxidative modifications of proteins and […]

The Connection of the Endocannabinoid System (ECS) and Exercise: The “Runner’s High”

A runner’s high is a sense of well-being some people experience after prolonged exercise. For decades, it was hypothesized that exercise-induced endorphin release is solely responsible for a runner’s high, but recent evidence has suggested that endocannabinoids also may play a role. A popular belief has been that endogenous endorphins mediate the effects of a […]

The Importance of the Endocannabinoid System (ECS) in Relation to Memory and PTSD Treatment

This study looks at conditions such as Post-Traumatic Stress Disorder (PTSD) as well as other conditions pertaining from fear, stress, and anxiety, through the targeting of Fatty Acid Amide Hydrolase (FAAH) to increase the efficiency of Anandamide’s (AEA) interactions with the ECS and different areas of the brain as a potential treatment for PTSD. Preclinical […]

The Potential Use of Cannabidiol for the Treatment of Obesity and Diabetes

In this study pertaining to cannabinoids and their potential usage as treatments for obesity and diabetes, CBD was looked at with particular interest in regards to any additional health issues that can come as a result of obesity in sites that have ties to the endocannabinoid system, namely the liver and the heart, however CBD’s […]

Study on the Effects of Cannabidiol for Sleep Issues and Anxiety

This study was looking at determining whether CBD helps improve sleep and/or anxiety in a clinical population. The sample initially consisted of 103 patients, however was reduced to 72 patients presenting primary concerns of anxiety (n=47) or poor sleep (n=25), where CBD was used as an adjunct to usual treatment. Nearly all patients were given […]

Cannabidiol’s Effect on the Hypothalamus-Pituitary-Adrenal Axis Under Stress Conditions

The aim of this research was to assess the effects of cannabidiol on different targets of the hypothalamus-pituitary-adrenal (HPA) axis under baseline stress conditions. Administered (5mg/kg, 15mg/kg, and 30mg/kg) 90 minutes before single restraint stress exposure, measurements were taken of alterations in the relative gene expressions of corticotropin-releasing factor in the paraventricular nucleus, pro-opiomelanocortin in […]

Re-set, Restore, Rejuvenate: How Can CBD Help Your Wellness Journey?

Many people consider health and wellness to be one and the same, and while they can impact each-other, they are still ultimately two different concepts. Health is more to do with a state of being, and how your body is operating, whereas wellness is more to do with your lifestyle, factoring in your surroundings and […]

Anxiety and Stress: Can CBD Help You Find Clarity Within Chaos?

In such a rapidly changing and connected world, being able to take a step back and breathe is a valuable ability to have. It allows us to look at an issue from a different perspective, or allows us to mentally prepare for a potentially stressful upcoming situation. Unfortunately that’s very much easier said than done […]

Finding Relief from Aches and Pains

Everyone at some point of their life will experience some aches and pain, and it could be because of a whole range of different reasons. For some of us, that would be a bit of muscle tension or soreness after a workout, for others it could be stiff joints due to arthritis, or it could […]

The Potential Benefits of CBD for Sleep

A good night’s sleep is considered essential to our health and wellbeing, and we all have our own evening rituals or habitual patterns, but are we getting enough sleep? Or more importantly, are we getting enough of the right type of rest? Sleep is an integral function for our body, allowing not only our body […]

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